Tumor Mutation Burden

Question

[adarsh_munna]

Hello,

I need to calculate the Tumor Mutation Burden for a Comprehensive Cancer Panel after calling the variants.

Is there any specific tool to do that?

Please suggest anything if available.

Thank You!

Answer 1

[Kevin Blighe]

What is tumour mutational burden? - a metric that can be easily modified to suit any bogus clinical test, which may or may not end up getting approval by a regulatory body.

Please take a look: How to calculate Tumor Mutation Burden (TMB) for TCGA samples

As you can see, one can easily calculate on one's own.

Kevin