What kind of libraries in Enrichr should I use?

Question

[pi]

I performed bulk RNA-seq using animal brain tissues with and without injury. Among DEGs from RNA-seq (injury vs control), I'd like to choose candidate genes involved with cellular changes after brain injury using Enrichr. As you know, however, there are many libraries about pathway (Bioplanet, Wikipathway, KEGG, etc.) and transcription (ChEA, ARCHS4, etc.) to analyze DEGs, so I can't decide what kind of library tool I should use for pathway/enrichment analysis. Could you please give me any information about that?

[sgallaher03]

Hi Pi,

I'm not sure about transcription but for pathways I've used Kegg, Reactome or MSigDB. Hope this helps.