Questions on Seurat AddModuleScore function
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3.0 years ago
Simon Ahn ▴ 10

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According to the manual, it says this function subtract the aggregated expression of control feature sets.

Does this mean I could only use up-regulated (or over-expressed) genes as features?

I'm trying to figure out which cells have the property of cancer stem cell, and I have the DEG list (compared with differentiated cancer cell)

AddModuleScore Seurat single-cell • 1.0k views
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