How to classify the SNPs/gene loci as reported or novel?

Question

[Mahan]

I have a big list of significant SNPs (>30K) from a GWAS/meta-analysis. Can you please suggest what are some best ways to find the respective gene names and further classify them as already reported and novel ones? Thanks in advance

Answer 1

[Ankit]

Use ANNOVAR or wANNOVAR

It annotate using several collection of databases. Assigned ones with rsID and other parameters (1000genome, gnomAD) are known. While unassigned could be novel ones.