Convertion of each bedGraph coverage into bigWig coverage not working

Question

[naloy]

Hi,

I'm getting this error while trying to convert bedGraph to bigWig in windows 10 (Chapter 4: RNA seq by example):

cat ids | parallel "bedGraphToBigWig bam/{}.bg  ${IDX}.fai bam/{}.bw"
bedGraphToBigWig: error while loading shared libraries: libssl.so.1.0.0: cannot open shared object file: No such file or directory
bedGraphToBigWig: error while loading shared libraries: libssl.so.1.0.0: cannot open shared object file: No such file or directory
bedGraphToBigWig: error while loading shared libraries: libssl.so.1.0.0: cannot open shared object file: No such file or directory
bedGraphToBigWig: error while loading shared libraries: libssl.so.1.0.0: cannot open shared object file: No such file or directory
bedGraphToBigWig: error while loading shared libraries: libssl.so.1.0.0: cannot open shared object file: No such file or directory
bedGraphToBigWig: error while loading shared libraries: libssl.so.1.0.0: cannot open shared object file: No such file or directory

Please help me.

Answer 1

[Pierre Lindenbaum]

if needed install the correct SSL library https://zoomadmin.com/HowToInstall/UbuntuPackage/libssl-dev

if needed fix the LD_LIBRARY_PATH https://stackoverflow.com/questions/7148036