Single-cell gene expression & chromatin accessibility integration?

Question

[tenderness.sunshine]

If my scRNA-seq & scATAC-seq are carried out on different cells (they're from same tissues), what's a better method to integrate these two data?

[antonioggsousa]

Hi,

I highly recommend that you read the recent paper benchmarking integration methods for scRNA-seq and scATAC-seq: Benchmarking atlas-level data integration in single-cell genomics

António

[Bastien Hervé]

As I understand you need diagonal integration, have a look on this paper