Missing normal samples in transcriptomic data from GDC portal

Question

[houssienali]

Hi, I downloaded a transcriptomic data from portal.gdc.cancer.gov for RNA-seq and my data from Ovary cancer include (primary tumor and recurrent tumor) samples, there's no normal samples.

is there any explanation for that ?! thanks

Answer 1

[Zhenyu Zhang]

Most cancer projects don't spend money sequencing normal transcriptome. You can go to GTEx for normals of unmatched patients