Validating splice site using protein sequence
0
0
Entering edit mode
2.9 years ago
praasu ▴ 40

Dear All,

I have assembled genome and RNA-seq with some novel protista genome. I have aligned the raw RNA-seq reads to genome and assembled the transcript using stringtie. So, I have gtf file. Now I want to validate the splice site using protein sequence from closing related species. I want to take only transcripts for the downstream analysis, whose splice sites are supported by protein evidence. Let me know if you have any suggestion for the same. Thank you very much in advance 😊

RNA-seq transcript assembly DNA-seq annotation • 609 views
ADD COMMENT
1
Entering edit mode

Why not just translate the regions and blast them?

ADD REPLY

Login before adding your answer.

Traffic: 1835 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6