Upset plot in ComplexHeatmap

Question

[Omics data mining]

Hello everyone

I am interested in developing the Upset plot for multiple sets of genes. I am using ComplexHeatmap R package for the Upset plot development. I have 49 sets for which I would like to highlight the interested count. I am using function make_comb_mat , but it gives me error

Error: Only support number of sets <= 31.

Has anyone experience this issue before?

I would appreciate all the suggestions.

Answer 1

[ATpoint]

It means the tool allows only up to 31 sets. And tbh, don't tell me that an upset with dozens of sets is informative. You get like hundreds of possible intersection combinations with that many sets.

[jared.andrews07]