Entering edit mode
2.8 years ago
hgalmoore
•
0
Hi,
I'm looking at a dataset that has two types of single-cell technology types. Roughly half the samples were run in SC3PV3 and half in SC3PV2. There seems to be a noticeable difference in UMAP in some populations that should be the same. My question is, is it okay to integrate on the 'single-cell type' parameter? I cant really find any info online on how V2 and V3 differ from each other.
scRNA-seq integration methods (e.g. Seurat integration, scVI, fastMNN, etc.) can integrate datasets from different sequencing technologies.