Expression of genes in KEGG pathway

Question

[nhaus]

I have performed a weighted correlation network analysis and have identified a set of genes which are correlated and highly expressed. I used the genes (~4000) in that set to perform an overrepresentation analysis to get an idea of their biological role. Among the KEGG pathways which were significantly overrepresented, were pathways such as Alzheimer Disease.

Now I am wondering, if there is a way to find out if the genes that overlap between my gene set, i.e. the ones from the identified module and the ones of the "Alzheimer Disease gene set" are regulated similarly. So, are the genes in the Alzheimer Disease KEGG pathway also highly expressed compared to healthy controls.

I greatly appreciate any advice you can give on the matter.

Cheers!

[seidel]

have identified a set of genes which are correlated and highly expressed.

So you know some of the Alzheimer Disease KEGG pathway genes are highly expressed in your data set...are you asking where you can find healthy control data? Or where you can query gene expression data in general? Does your experiment not include healthy and diseased individuals? What data set(s) is your network based on?