GISTIC Score Calculation for CNV Dataset in Cell Model Passports Database
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2.7 years ago
Yean ▴ 140

Hi all,

In Cell Model Passports database, I am wondering how the GISTIC score is calculated for all gene in each cell line in the CNV dataset that is derived from affymetrix snp 6.0 arrays?. The overview of CNV dataset can be found in this link

As far as i understand, the GISTIC score is calculated for the specific region in the genes, calculated by

G score = cnv_frequency_across_sample * average_amplitude

At this point, I am not sure how the GISTIC score in CNV dataset is calculated. Did they use the same formula that i just show or use the different one for GISTIC score calculation for each cell line in CNV dataset ?

Thanks,

Yean

Cell Passport GISTIC Model • 530 views
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