How to count STRs
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2.7 years ago
McKenna • 0

How do you count insertions when there they are heterogeneous?

Insertion (16 bases): TATATATATATATATA
Insertion (6 bases): TATATA

What would be the count?

STR • 701 views
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This question is a little too vague for a meaningful answer. What is it that you would like to count? For what purpose are you counting it? You could say you have 2 insertions of size 6 and 16. Do you have reason to believe these insertions need some factorization? (for instance, if you have a process that inserts the dinucleotide TA and you need to count iterations per event).

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Hi thanks for the reply I looking into this:

Prostate Cancer Risk and ESR1 TA, ESR2 CA Repeat Polymorphisms

https://dash.harvard.edu/handle/1/41292894

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