How do I find the most common mutations in a MAF dataset?
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2.8 years ago

How do I find the most common mutations in a MAF dataset? Should I use pfamDomains from maftools?

library(maftools)

d <- merge_mafs(lapply(Sys.glob("mafs/Patient*.maf"), read.maf))

d.pfam = pfamDomains(maf=d, AACol="Protein_Change", top=15)
d.pfam$proteinSummary[,1:7, with=FALSE]
maftools maf mutation • 541 views
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