Hello to everyone. I am new to bioinformatics and I have a beginners question. What can I do with low quality reads. The only thing that I found out so far is that I can trim off the low quality part of the read. Is it something else that I can do to clean up the data? Is there any rule of how much I can trim a read?
Thanks in advance!
Worry more about what to do with good quality reads :-)
Few if any analyses are severely impacted merely because the data recovery could have been done better. Even the simplest tasks you undertake will fix 90% of problems, so the best to move onto the main tasks.
In a nutshell run fastp and it will take care of most problems for you
Got it! Thanks a lot for your help Istvan