Are multiple-testing correction required to construct a network using mixOmics to integrate data from two omics?

Question

[xiaoxiao]

Hi all, I am now using the mixOmics package to integrate the two omic datasets, the sPLS-DA (sparse PLS-DA) model is executed to test whether a set of variables can distinguish the groups and the similarity values between pair of variables are calculated by the network function. Do multiple-testing correction need during this process?

Answer 1

[lorenzo.campanelli11]

No because you are doing a exploratory analysis. You will be observing how de variables describe your subjects. You wont be proofing an hypothesis.