What does it mean by "conformational space"?

Question

[user366312]

• SURPASS Low-Resolution Coarse-Grained Protein Modeling

The method samples a significant part of conformational space and reproduces protein structures, including native-like, with surprisingly good accuracy.

What does it mean by "conformational space"?

[fracarb8]

conformational space is the imaginary space that contains every possible conformation of a given molecule. It is of infinite size, and it is impossible to explore all the possible conformation. Software like the one you linked, sample the areas of this space exploring only the structure with biological relevance (e.g. low energy structure).