monoallelic expression analysis

Question

[Sara]

I am trying to perform monoallelic expression analysis (MAE) but have not found a suitable pipeline for it. would someone recommend me a pipeline for MAE?

Answer 1

[nux]

Maybe you can try this one https://github.com/gagneurlab/drop

Answer 2

[Fabio Marroni]

Monoallelic expression can be seen as an extreme instance of allele specific expression. Among the tools that are out for this, I used Allim and contributed to the development of BayesASE. I like very much (of course!) the tool I helped developing, but you need some skills in managing moab scheduling systems to fully exploit it.