Count number of times a value appear in correlation matrix
0
0
Entering edit mode
2.6 years ago
ali ▴ 20

Hi everyone, I might be not really good with R but I really don't get this thing : I have a matrix of 2590 x 2590 genes (correlation matrix) with values between -1.0 and 1.0 and with a diagonal of all 1.0s , easily obtained with the following function (that returns 2590) :

sum(diag(cor.matrix))

Now when I do further analysis such as ( Fisher transformation ) I get 1640 infinite (Because of the division on zero) but this means that he only see 1640 1.0s instead of 2590, in fact if I do the following :

sum(cor.matrix==1)

It instead gets wrong telling me they are only 1640, and thats a huge problem, how is possible that I get 2590 1.0s but it sees only 1640 with another function?.

I add that with :

table(unlist(cor.matrix))

I get actually that 2572 are 1.0s and 12 are 0.99999, but still I don't get why 1640.

correlation R cor • 1.4k views
ADD COMMENT
0
Entering edit mode

Please show the output of str(cor.matrix). Also, how did you produce cor.matrix?

ADD REPLY
0
Entering edit mode

cor.matrix was generated by the function cor(t(data)) where data has genes as rows and samples as columns. And below is the output of str(cor.matrix) :

>  str(cor.matrix)
num [1:2590, 1:2590] 0 0.6554 0.0337 0.0265 -0.3639 ...
- attr(*, "dimnames")=List of 2
..$ : chr [1:2590] "ENSG00000104763" "ENSG00000023697" "ENSG00000108848" "ENSG00000159140" ...
..$ : chr [1:2590] "ENSG00000104763" "ENSG00000023697" "ENSG00000108848" "ENSG00000159140" ...
ADD REPLY
0
Entering edit mode

I think you should explain your "Fisher transformation", which code did you use ?

ADD REPLY
0
Entering edit mode

The Fisher transformation is applied after so it has nothing to do with it ( my bad I mentioned it ). My concern is why and how is possible that when I type table(unlist(cor.matrix)) It returns me that I have 2572 "1" and 12 "0.99" (that are those in the Diagonal) and when I type sum(cor.matrix==1) instead it gives me 1640?

ADD REPLY
0
Entering edit mode

Give us an example subset, dput(cor.matrix[1:10, 1:10]), ensure this includes both 1s and 0.99s rows/cols. By the way unlist does nothing on matrix, matrix is not a list.

ADD REPLY
0
Entering edit mode

Thank you for your reply , actually there are no 0.99 in the diagonal as I checked with diag(), so here is a subset of 10x10 :

> cor.matrix
                ENSG00000112077 ENSG00000156381 ENSG00000104903 ENSG00000115457 ENSG00000206549 ENSG00000137267 ENSG00000185340 ENSG00000170323
ENSG00000112077     1.000000000     -0.19190013      -0.1966784     -0.13290891     0.002734867     -0.08534596     -0.17967079       0.4426268
ENSG00000156381    -0.191900129      1.00000000       0.9095771      0.51786695    -0.022457054     -0.16575985      0.93824489      -0.2583800
ENSG00000104903    -0.196678419      0.90957714       1.0000000      0.53893050    -0.023318702     -0.22419045      0.90572245      -0.2714970
ENSG00000115457    -0.132908908      0.51786695       0.5389305      1.00000000    -0.124795340     -0.04742099      0.46764793      -0.1230762
ENSG00000206549     0.002734867     -0.02245705      -0.0233187     -0.12479534     1.000000000     -0.17214213      0.06069934      -0.1768969
ENSG00000137267    -0.085345957     -0.16575985      -0.2241905     -0.04742099    -0.172142132      1.00000000     -0.14076607       0.1460344
ENSG00000185340    -0.179670795      0.93824489       0.9057225      0.46764793     0.060699339     -0.14076607      1.00000000      -0.2571831
ENSG00000170323     0.442626760     -0.25838000      -0.2714970     -0.12307625    -0.176896861      0.14603436     -0.25718315       1.0000000
ENSG00000101425     0.902741312     -0.16307465      -0.1615747     -0.02066323     0.043884391     -0.09102911     -0.16472355       0.4715138
ENSG00000103316     0.288357227     -0.37126758      -0.3712558     -0.39090657     0.177580855     -0.22241386     -0.38319491       0.1151637
                ENSG00000101425 ENSG00000103316
ENSG00000112077      0.90274131       0.2883572
ENSG00000156381     -0.16307465      -0.3712676
ENSG00000104903     -0.16157472      -0.3712558
ENSG00000115457     -0.02066323      -0.3909066
ENSG00000206549      0.04388439       0.1775809
ENSG00000137267     -0.09102911      -0.2224139
ENSG00000185340     -0.16472355      -0.3831949
ENSG00000170323      0.47151380       0.1151637
ENSG00000101425      1.00000000       0.1689805
ENSG00000103316      0.16898054       1.0000000

Diagonal for easier visualization :

diag(cor.matrix) #diagonal
ENSG00000112077 ENSG00000156381 ENSG00000104903 ENSG00000115457 ENSG00000206549 ENSG00000137267 ENSG00000185340 ENSG00000170323 ENSG00000101425 
              1               1               1               1               1               1               1               1               1 
ENSG00000103316 
          1 

Here are instead the info about the full matrix :

> ncol(cor.matrix) #length col
[1] 2590
> nrow(cor.matrix) #length row
[1] 2590
> summary(colnames(cor.matrix)==rownames(cor.matrix))
   Mode    TRUE 
logical    2590 
> sum(diag(cor.matrix))
[1] 2590

sum(diag(cor.matrix)) says 2590 that means that all the diagonal present the number 1.000000 , so I dont get how is possible I retrive 1640 from the function sum(cor.matrix==1).

ADD REPLY
0
Entering edit mode

Please provide the output of dput(df)instead of printing the data frame, it is difficult to recreate your object for us otherwise

ADD REPLY
0
Entering edit mode
    > dput(cor.matrix)
    structure(c(1, -0.191900129370209, -0.19667841893541, -0.132908907990152, 
    0.00273486675878516, -0.0853459574505116, -0.179670794954244, 
    0.442626760071414, 0.90274131194274, 0.288357226535195, -0.191900129370209, 
    1, 0.9095771369306, 0.517866950532572, -0.0224570543574054, -0.165759851161471, 
    0.938244885408117, -0.258380001065272, -0.163074651868828, -0.371267577550608, 
    -0.19667841893541, 0.9095771369306, 1, 0.538930500368628, -0.023318702025332, 
    -0.22419045064296, 0.905722451573056, -0.271497014948629, -0.161574724589497, 
    -0.371255805716392, -0.132908907990152, 0.517866950532572, 0.538930500368628, 
    1, -0.124795340475141, -0.0474209907792123, 0.467647928811358, 
    -0.123076247648689, -0.0206632281207981, -0.390906566893226, 
    0.00273486675878516, -0.0224570543574054, -0.023318702025332, 
    -0.124795340475141, 1, -0.172142131502174, 0.0606993394920817, 
    -0.176896861113167, 0.0438843914074129, 0.177580854744091, -0.0853459574505116, 
    -0.165759851161471, -0.22419045064296, -0.0474209907792123, -0.172142131502174, 
    1, -0.140766069991547, 0.14603436439314, -0.0910291108101076, 
    -0.222413862352161, -0.179670794954244, 0.938244885408117, 0.905722451573056, 
    0.467647928811358, 0.0606993394920817, -0.140766069991547, 1, 
    -0.257183149502409, -0.164723552108329, -0.383194913178383, 0.442626760071414, 
    -0.258380001065272, -0.271497014948629, -0.123076247648689, -0.176896861113167, 
    0.14603436439314, -0.257183149502409, 1, 0.471513802606508, 0.115163716714095, 
    0.90274131194274, -0.163074651868828, -0.161574724589497, -0.0206632281207981, 
    0.0438843914074129, -0.0910291108101076, -0.164723552108329, 
    0.471513802606508, 1, 0.168980542895039, 0.288357226535195, -0.371267577550608, 
    -0.371255805716392, -0.390906566893226, 0.177580854744091, -0.222413862352161, 
    -0.383194913178383, 0.115163716714095, 0.168980542895039, 1), 
.Dim = c(10L, 
    10L), 
.Dimnames = list(c("ENSG00000112077", "ENSG00000156381", 
    "ENSG00000104903", "ENSG00000115457", "ENSG00000206549", "ENSG00000137267", 
    "ENSG00000185340", "ENSG00000170323", "ENSG00000101425", "ENSG00000103316"
    ), c("ENSG00000112077", "ENSG00000156381", "ENSG00000104903", 
    "ENSG00000115457", "ENSG00000206549", "ENSG00000137267", "ENSG00000185340", 
    "ENSG00000170323", "ENSG00000101425", "ENSG00000103316")))
ADD REPLY
0
Entering edit mode

This example data give the 10 for both, provide bigger example data where this is not true. Or upload the full file somewhere and share the link:

sum(diag(cor.matrix)) 
# [1] 10
sum(cor.matrix==1)
# [1] 10
ADD REPLY

Login before adding your answer.

Traffic: 2933 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6