Question

How to search and identify the function of DEGs

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2.5 years ago

Roy.anupama11 • 0

How to retrieve and identify the function of DEGs? What are the different types of tools available?

function functional annoatation DEGs • 676 views

ADD COMMENT • link updated 2.5 years ago by Marco Pannone ▴ 810 • written 2.5 years ago by Roy.anupama11 • 0

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If you refer to pathways/GO analysis, I would recommend GSEA.

ADD REPLY • link 2.5 years ago by Marco Pannone ▴ 810

score 0 · Answer 1 · 2022-05-23

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2.5 years ago

rachel.walters.18 • 0

For GO/pathway analysis and GSEA (as mentioned in a previous reply) I've always found webgestalt really easy to use.

ADD COMMENT • link 2.5 years ago by rachel.walters.18 • 0

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On WebGestalt you perform a pre-ranked GSEA, where you input already computed logFC values for each gene. In a proper GSEA you instead input a matrix or normalized read counts with all genes as rows and all replicates as columns.

ADD REPLY • link 2.5 years ago by Marco Pannone ▴ 810