Hello!
I have done a Big Y ftdna and I want to upload a Bam file into yfull. I saw that I need 100$ to generate a Bam file with ftdna. It's too expansive for me! Is there any solution to generate a Bam file with a VCF 4.1 ftdna file please?
Thanks for your reply.
There's no way of doing this, since going from .bam -> .vcf necessarily loses a lot of information.
Are you sure you can't upload the data in vcf format?
To explain the why: VCF files may be generated by two different assays - Genotyping and Sequencing.
While the former costs a company in the range of 50$ in material and personnel costs, the latter is in the range of 200$-500$, depending on the amount of data generated. Business models vary, such that a company may ask a customer to pay the full price upfront or initially offer lower prices to later charge for additional services.
.bam files store sequencing data and when a VCF file is generated from it, a lot of information is lost: Imagine a high resolution photo taken by your camera that you scale down to 100px. You can not go back from there to a detailed 5000px image again. You can maybe impute information, but not bring the original information back.
Therefore: Whatever you do now, even if you manage to create a *.bam file, the genetic correspondences will not improve over the VCF that you already have. In case you ordered a sequencing, the more detailed information is on record, but you will not get access to it without covering the additional costs.
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version 2.3.6
see vcf to bam
Ok Pierre, I will read this link! Thanks!