Likelihood that increase is not by chance

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2.5 years ago

Lasha ▴ 10

I saw that in protein-coding genes there are some genes more frequent than expected. How can I estimate the likelihood that this increase is not by chance?

I have the ability to estimate individual chromosomes by these criteria. 22 out of 23 chromosomes had such kind of increase and Wilcoxon Signed-Rank Test gave me p<0.000288, but I can't interpret this result nor can understand if it gains more persuasiveness to the fact, that difference is real.

UPDATE: Mouse gives the same increase for 19 out of 20 chromosomes

research-tools research-design genes biostatistics statistics • 780 views

ADD COMMENT • link 2.5 years ago by Lasha ▴ 10

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What do you mean exactly when you say that some protein coding genes are more frequent than expect?

ADD REPLY • link 2.5 years ago by rpolicastro 13k

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I've found that mitochondrial genes tend to overlap more frequently on human and mouse genomes than any genes do overlap. enter image description here

Then I checked it for every chromosome and it is the case for every chromosome.

Hope I answered your question.

ADD REPLY • link 2.5 years ago by Lasha ▴ 10

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