What's the full list of UniProt topological domain types?

Question

[ngarber]

Quick question - in UniProt REST text entries (e.g. https://rest.uniprot.org/uniprotkb/Q9UBP0.txt), there are 3 types of topological domains I know about.

TOPO_DOM, TRANSMEM, and INTRAMEM. Are there any others, or is that it?

I want to make sure my script doesn't miss any of them. For TOPO_DOM, I know I have to look at the next line to see which compartment it faces.

[Rafael Soler]

I'm pretty sure it is, but if in doubt, you can download all the proteins of a species in a csv file and do a search for unique elements in the topological domains column.

Best

Answer 1

[Elisabeth Gasteiger]

The topological domains can have the values listed here: https://www.uniprot.org/help/topo_dom

TRANSMEM and INTRAMEM are documented in

https://www.uniprot.org/help/transmem

https://www.uniprot.org/help/intramem

respectively.

Please don't hesitate to contact the UniProt helpdesk via the contact form on the website.

[ngarber]

Thanks so much, this is what I needed!