Problem while uploading DESeq2 library

Question

[Amr]

Problem while uploading DESeq2 library:

library(DESeq2) Loading required package: GenomicRanges Loading required package: GenomeInfoDb Error: package or namespace load failed for ‘GenomeInfoDb’ in loadNamespace(i, c(lib.loc, .libPaths()), versionCheck = vI[[i]]): there is no package called ‘GenomeInfoDbData’ Error: package ‘GenomeInfoDb’ could not be loaded

Please help Thanks in advance

[cpad0112]

 there is no package called ‘GenomeInfoDbData’

try installing that package. Then try loading package ‘GenomeInfoDb’

[Amr]

I tried to install GenomeInfoDbData by this below command:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

# The following initializes usage of Bioc devel
BiocManager::install(version='devel')

BiocManager::install("GenomeInfoDbData")

I got that message although I cant find that directory C:\Users\Amr\AppData\Local\Temp\RtmpWiEsQe\downloaded_packages:

Error in setwd(exdir) : cannot change working directory Warning in install.packages(...) : installation of package ‘GenomeInfoDbData’ had non-zero exit status

The downloaded source packages are in ‘C:\Users\Amr\AppData\Local\Temp\RtmpWiEsQe\downloaded_packages’ Installation paths not writeable, unable to update packages path: C:/Program Files/R/R-4.2.1/library packages: nlme Old packages: 'IRanges', 'S4Vectors' Update all/some/none? [a/s/n]:

[Basti]

Have your tried to close and reload your R session ? After you can try to reinstall

[Amr]

Solved !! by run Rstudio as adminstrator and the packages are installed smoothly.

[cpad0112]

That is a problem. Every time you install a package, you will have to run Rstudio as admin. Try configuring user directory for library installation.