The Biostar Herald publishes user submitted links of bioinformatics relevance. It aims to provide a summary of interesting and relevant information you may have missed. You too can submit links here.
This edition of the Herald was brought to you by contribution from Istvan Albert, and was edited by Istvan Albert,
GitHub - matloff/TidyverseSkeptic: An opinionated view of the Tidyverse "dialect" of the R language. (github.com)
Teaching R in a Kinder, Gentler, More Effective Manner: Use Base-R, Not the Tidyverse
submitted by: Istvan Albert
GitHub - matloff/R-vs.-Python-for-Data-Science (github.com)
This Web page is aimed at shedding some light on the perennial R-vs.-Python debates in the Data Science community. As a professional computer scientist and statistician, I have a foot in both camps, and I hope to shed some useful light on the topic.
submitted by: Istvan Albert
Human Capital Mediates Natural Selection in Contemporary Humans | SpringerLink (link.springer.com)
We test for natural selection through the association between 33 polygenic scores and fertility, across two generations, using data from UK Biobank (N = 409,629 British subjects with European ancestry). Consistently over time, polygenic scores that predict higher earnings, education and health also predict lower fertility.
submitted by: Istvan Albert
A Draft Human Pangenome Reference | bioRxiv (www.biorxiv.org)
The Human Pangenome Reference Consortium (HPRC) presents a first draft human pangenome reference. The pangenome contains 47 phased, diploid assemblies from a cohort of genetically diverse individuals. These assemblies cover more than 99% of the expected sequence and are more than 99% accurate at the structural and base-pair levels.
submitted by: Istvan Albert
getSequenceInfo: a suite of tools allowing to get genome sequence information from public repositories | BMC Bioinformatics | Full Text (bmcbioinformatics.biomedcentral.com)
The aim of this study is to democratize the use of public repositories in programmatic ways, and to facilitate sequence data analysis in a pedagogical perspective. Output results are available in FASTA, FASTQ, Excel/TSV or HTML formats. The program is freely available at: https://github.com/karubiotools/getSequenceInfo.
submitted by: Istvan Albert
https://academic.oup.com/nar/article/50/W1/W1/6627157
This is the 20th edition of the Nucleic Acids Research Web Server Issue.
We received 301 proposals describing new or updated web servers and stand-alone tools this year. One hundred thirty-three were invited to submit a manuscript, 102 (77%) of the submissions were accepted, leading to an acceptance rate of one third of the initial proposals.
submitted by: Istvan Albert
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