Entering edit mode
2.3 years ago
Raju
•
0
Hello, I have calculated LD for a set of SNPs of a specific Gene using the below command:
plink --bfile Obesity --allow-no-sex --extract ADRA2A_SNPs.txt --r2 --out LD_file
Output:
CHR_A BP_A SNP_A CHR_B BP_B SNP_B R2
10 112340060 kgp11784838 10 112349204 kgp7971364 0.268577
10 112340060 kgp11784838 10 112349422 kgp5177378 1
10 112340060 kgp11784838 10 112349879 rs3737294 0.27927
10 112343591 rs11195199 10 112349204 kgp7971364 0.630264
10 112343591 rs11195199 10 112349879 rs3737294 0.681088
10 112349204 kgp7971364 10 112349422 kgp5177378 0.268577
10 112349204 kgp7971364 10 112349879 rs3737294 0.936585
10 112349422 kgp5177378 10 112349879 rs3737294 0.27927
10 112349602 rs3737293 10 112353346 kgp22819565 0.946159
Now, I would like to obtain all SNPs that are in high linkage disequilibrium (LD) for a set of all SNPs with threshold LD (r2 > 0.6) for a list of SNPs.