What Is The Best Method To Find Orthologous Genes Of One Species And Compare With Another Species?

Question

[logbio]

I want to know which is the best tool and best database if I want to find ortholog genes of all human genes, homo sapiens in c.elegans etc.

Thank you for answering

[Friederike]

I am not aware of a benchmark study that would allow me to pinpoint the best resource, but a very good one that I use frequently is https://www.ncbi.nlm.nih.gov/guide/homology/ The "how to" explains a single-gene/protein search, you can download the full table at HomoloGene though.