Trouble with inferring genetic relation using KING
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2.2 years ago
nanodano ▴ 30

Hi everyone,

I'm using KING (manual here) to infer genetic relatedness in my dataset. I know there are relatives in the data set based on ethnographic interviews.

I have been running the following KING command to output a .seg file that should contain relations across each pair of individuals in the dataset. king -b data.bed --ibdseg --prefix data_ibdseg ... Although, it's outputting mostly UN (unrelated) across all samples, which, in my case, should definitely not happen to this extent. I'm not sure what is going on, has anyone encountered this and can help? Any suggestions at all is appreciated, not sure where to start looking.

ibs ibd relatives king genetic • 426 views
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