GDCprepare truncated when downloading TCGA methylation data
0
0
Entering edit mode
2.2 years ago

I want to download the methylation data of the TCGA-KIRC project using GDCquery and GDCprepare. My code raised a warning message that implies that the GDCprepare step is truncated, with the "Warning message: In open.connection(con, "rb") : ... [... truncated]" message. What is the solution?

query.met.kirc <- GDCquery(
  project = "TCGA-KIRC", 
  legacy = TRUE,
  data.category = "DNA methylation",
  platform = "Illumina Human Methylation 450", 
)
GDCdownload(query.met.kirc)

met.kirc.450 <- GDCprepare(
  query = query.met.kirc,
  save = TRUE, 
  save.filename = "kircDNAmet450k.rda",
  summarizedExperiment = TRUE
)

Warning message:

--------------------
oo Merging 485 files
--------------------
Starting to add information to samples
 => Add clinical information to samples
 => Adding TCGA molecular information from marker papers
 => Information will have prefix 'paper_' 
kirc subtype information from:doi:10.1038/nature12222
=> Saving file: kircDNAmet450k.rda
=> File saved
Warning message:
In open.connection(con, "rb") :
  URL 'https://api.gdc.cancer.gov/cases/?pretty=true&expand=samples,project,diagnoses,diagnoses.treatments,annotations,family_histories,demographic,exposures&size=10&filters=%7B%22op%22:%22or%22,%22content%22:[%7B%22op%22:%22in%22,%22content%22:%7B%22field%22:%22cases.submitter_id%22,%22value%22:["TCGA-BP-4993-01A","TCGA-CZ-5982-01A","TCGA-B0-4703-01A","TCGA-CJ-4908-01A","TCGA-CZ-5470-11A","TCGA-B0-4811-01A","TCGA-BP-5183-11A","TCGA-DV-5574-01A","TCGA-CZ-5451-01A","TCGA-B0-5099-11A%22]%7D%7D,%7B%22op%22:%22in%22,%22content%22:%7B%22field%22:%22submitter_sample_ids%22,%22value%22:["TCGA-BP-4993-01A","TCGA-CZ-5982-01A","TCGA-B0-4703-01A","TCGA-CJ-4908-01A","TCGA-CZ-5470-11A","TCGA-B0-4811-01A","TCGA-BP-5183-11A","TCGA-DV-5574-01A","TCGA-CZ-5451-01A","TCGA-B0-5099-11A%22]%7D%7D,%7B%22op%22:%22in%22,%22content%22:%7B%22field%22:%22submitter_aliquot_ids%22,%22value%22:["TCGA-BP-4993-01A","TCGA-CZ-5982-01A","TCGA-B0-4703-01A","TCGA-CJ-4908-01A","TCGA-CZ-5470-11A","TCGA-B0-4811-01A","TCGA-BP-51 [... truncated]
GDCquery GDCprepare R TCGA • 433 views
ADD COMMENT

Login before adding your answer.

Traffic: 2034 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6