Entering edit mode
2.2 years ago
melissachua90
▴
70
I want to download the methylation data of the TCGA-KIRC project using GDCquery and GDCprepare. My code raised a warning message that implies that the GDCprepare step is truncated, with the "Warning message: In open.connection(con, "rb") : ... [... truncated]" message. What is the solution?
query.met.kirc <- GDCquery(
project = "TCGA-KIRC",
legacy = TRUE,
data.category = "DNA methylation",
platform = "Illumina Human Methylation 450",
)
GDCdownload(query.met.kirc)
met.kirc.450 <- GDCprepare(
query = query.met.kirc,
save = TRUE,
save.filename = "kircDNAmet450k.rda",
summarizedExperiment = TRUE
)
Warning message:
--------------------
oo Merging 485 files
--------------------
Starting to add information to samples
=> Add clinical information to samples
=> Adding TCGA molecular information from marker papers
=> Information will have prefix 'paper_'
kirc subtype information from:doi:10.1038/nature12222
=> Saving file: kircDNAmet450k.rda
=> File saved
Warning message:
In open.connection(con, "rb") :
URL 'https://api.gdc.cancer.gov/cases/?pretty=true&expand=samples,project,diagnoses,diagnoses.treatments,annotations,family_histories,demographic,exposures&size=10&filters=%7B%22op%22:%22or%22,%22content%22:[%7B%22op%22:%22in%22,%22content%22:%7B%22field%22:%22cases.submitter_id%22,%22value%22:["TCGA-BP-4993-01A","TCGA-CZ-5982-01A","TCGA-B0-4703-01A","TCGA-CJ-4908-01A","TCGA-CZ-5470-11A","TCGA-B0-4811-01A","TCGA-BP-5183-11A","TCGA-DV-5574-01A","TCGA-CZ-5451-01A","TCGA-B0-5099-11A%22]%7D%7D,%7B%22op%22:%22in%22,%22content%22:%7B%22field%22:%22submitter_sample_ids%22,%22value%22:["TCGA-BP-4993-01A","TCGA-CZ-5982-01A","TCGA-B0-4703-01A","TCGA-CJ-4908-01A","TCGA-CZ-5470-11A","TCGA-B0-4811-01A","TCGA-BP-5183-11A","TCGA-DV-5574-01A","TCGA-CZ-5451-01A","TCGA-B0-5099-11A%22]%7D%7D,%7B%22op%22:%22in%22,%22content%22:%7B%22field%22:%22submitter_aliquot_ids%22,%22value%22:["TCGA-BP-4993-01A","TCGA-CZ-5982-01A","TCGA-B0-4703-01A","TCGA-CJ-4908-01A","TCGA-CZ-5470-11A","TCGA-B0-4811-01A","TCGA-BP-51 [... truncated]