Databases with Genes <-> Diseases relations

Question

[Alexander]

Warning Genes may be involved in diseases in various various ways which is difficult to put in databases (I know that), still for starting point:

Question What are databases (with possibly Python interfaces) which describe genes <-> diseases relations ? What are the survey papers on that topic ?

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My feeling that information is somewhat scattered, hopefully I am wrong.

Some examples of scattered information:

For ALS ((Amyotrophic lateral sclerosis) - see here https://alsod.ac.uk/ (some notebook describing genes interacting with them https://www.kaggle.com/code/alexandervc/genes-interacting-with-als-genes)

For e.g. Ewing Sarcoma - Ewing sarcoma "related" genes ?

And so on.

Answer 1

[Ribo]

DISEASES is a web resource that integrates evidence on disease-gene associations from automatic text mining, manually curated literature, cancer mutation data, and genome-wide association studies.

Answer 2

[tomc]

OMIM for the single gene disorders https://www.omim.org/

https://www.disgenet.org/ exists

Use cases make a one size fits all highly unlikely

Answer 3

[cmdcolin]

ClinGen https://search.clinicalgenome.org/kb/gene-validity

GenCC https://thegencc.org/

[cmdcolin]

nice twitter account with papers related to disease genes too https://twitter.com/DiseaseGenes