What can I do after enrichment of expression microarray?

Question

[Di Wu]

Hello everyone,

1. Now I have a number of mRNA expression microarray which from blood in mouse disease model. After I analyse DEGs and function enrichment, I find some genes related with disease. Then I check it in GEO database (which is from blood of human) and validate our results in this dataset. But I plan to do further more. I check many paper, mostly were focused on wet lab. Is there some dry lab for me to do with them?
2. If I'm only interest in some genes(nearly 100), can i just filter the expression to only these genes and do the DEGs via limma? I think it may increase the statistic power or not? Thank you