Entering edit mode
2.2 years ago
igor
13k
Enrichr includes many gene set libraries. Many of them are very obvious based on the name, such as BioCarta_2016 or KEGG_2016. However, some are more ambiguous. For example, ClinVar_2019 is presumably based on ClinVar, but that is not a pathway database, so some extra processing had to occur. It's probably based on recurrent variants in particular diseases, but it's not clear. Is there a way to look up how each gene set library was generated? The help section is very nice, but this part doesn't appear to be there.
Sounds like this may be a question for the developers of Enrichr (via GitHub?).
I'm interested in exactly the same question, hard to base any conclusions on the library if you don't understand how it was generated. I found this github thread and added my comment, would be great if you can join as well, maybe we will get the information if there is increased demand from the users:
https://github.com/MaayanLab/enrichr_issues/issues/10
Looks like you already got a response there. Unfortunately, it was only for your particular gene set of interest. It sounds like there isn't some kind of organized table available anywhere.
There is none at this moment, but according to the developers they plan to create ETL Appyters for each library. Probably, your best option is to ask precisely about particular library if you need it asap.
Appyters are great, but I am not necessarily trying to recreate the gene sets. I just want a simple description, which should be a lot easier to put together. If someone asks about a particular gene set in a live meeting, I would like to be able to immediately respond with an answer.