Seurat installation errors (configure: error: geos-config not found or not executable & ERROR: dependency; no sudo)

Question

[sasa]

I need to install the Seurat package

I'm trying to install Seurat on CentOS Linux 7, but I can't. I am getting several error messages:

• configure: error: geos-config not found or not executable.
• ERROR: configuration failed for package ‘rgeos’
• ERROR: dependency ‘rgeos’ is not available for package ‘SeuratObject’
• ERROR: dependency ‘SeuratObject’ is not available for package ‘Seurat’

I do not have sudo permission, so I can't run the codes such as sudo apt install libgeos-dev

The situation is very similar to this issue (no practical solution)

I would be grateful if anyone could help me to install Seurat.

Any comments and suggestions would be very much appreciated.

Below are the details:

install.packages("Seurat")

And I got:

Installing package into ‘/home/users/myname/R_libs’ (as ‘lib’ is unspecified) also installing the dependencies ‘rgeos’, ‘SeuratObject’

trying URL 'https://ftp.osuosl.org/pub/cran/src/contrib/rgeos_0.5-9.tar.gz' Content type 'application/x-gzip' length 290240 bytes (283 KB) ================================================== downloaded 283 KB

trying URL 'https://ftp.osuosl.org/pub/cran/src/contrib/SeuratObject_4.1.2.tar.gz' Content type 'application/x-gzip' length 194969 bytes (190 KB) ================================================== downloaded 190 KB

trying URL 'https://ftp.osuosl.org/pub/cran/src/contrib/Seurat_4.2.0.tar.gz' Content type 'application/x-gzip' length 1467764 bytes (1.4 MB) ================================================== downloaded 1.4 MB

• installing source package ‘rgeos’ ... package ‘rgeos’ successfully unpacked and MD5 sums checked using staged installation configure: CC: gcc configure: CXX: c++ configure: rgeos: 0.5-9 checking for /usr/bin/svnversion... no configure: svn revision: 684 checking for geos-config... no no configure: error: geos-config not found or not executable. ERROR: configuration failed for package ‘rgeos’
• removing ‘/home/users/myname/R_libs/rgeos’ ERROR: dependency ‘rgeos’ is not available for package ‘SeuratObject’
• removing ‘/home/users/myname/R_libs/SeuratObject’ ERROR: dependency ‘SeuratObject’ is not available for package ‘Seurat’
• removing ‘/home/users/myname/R_libs/Seurat’

The downloaded source packages are in ‘/tmp/RtmpeoMwdn/downloaded_packages’ Warning messages: 1: In install.packages("Seurat") : installation of package ‘rgeos’ had non-zero exit status 2: In install.packages("Seurat") : installation of package ‘SeuratObject’ had non-zero exit status 3: In install.packages("Seurat") : installation of package ‘Seurat’ had non-zero exit status

sessionInfo()

R version 4.2.0 (2022-04-22) Platform: x86_64-pc-linux-gnu (64-bit) Running under: CentOS Linux 7 (Core)

Matrix products: default BLAS/LAPACK: /share/software/user/open/openblas/0.3.10/lib/libopenblas_haswellp-r0.3.10.so

locale: 1 LC_CTYPE=en_US.UTF-8 LC_NUMERIC=C
[3] LC_TIME=en_US.UTF-8 LC_COLLATE=en_US.UTF-8
[5] LC_MONETARY=en_US.UTF-8 LC_MESSAGES=en_US.UTF-8
[7] LC_PAPER=en_US.UTF-8 LC_NAME=C
[9] LC_ADDRESS=C LC_TELEPHONE=C
[11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C

attached base packages: 1 stats graphics grDevices utils datasets methods base

other attached packages: 1 ggplot2_3.4.0

loaded via a namespace (and not attached): 1 fansi_1.0.3 withr_2.5.0 dplyr_1.0.10 utf8_1.2.2
[5] grid_4.2.0 R6_2.5.1 lifecycle_1.0.3 gtable_0.3.1
[9] magrittr_2.0.3 scales_1.2.1 pillar_1.8.1 rlang_1.0.6
[13] cli_3.4.1 generics_0.1.3 vctrs_0.5.0 tools_4.2.0
[17] glue_1.6.2 munsell_0.5.0 compiler_4.2.0 pkgconfig_2.0.3 [21] colorspace_2.0-3 tidyselect_1.2.0 tibble_3.1.8

[rpolicastro]

If you don't have sudo permissions you may want to consider installing the software via conda.

[Aryan]

https://stackoverflow.com/questions/31388102/install-r-in-linux-unix-without-having-root-privilage - as the other user also commented

[sasa]

Hi, thank you for your suggestions. I have tried with conda but kept getting similar errors. However, I have solved the problems. It was a missing library and a compiler-related problem. My environment is an institutional HPC cluster, and I should have followed a module system to install Seurat. I referred to another institute's website. Again thanks for your helpful suggestions, rpolicastro and Aryan

[Aryan]

Thanks for sharing that! I also work on an HPC cluster and your link is very helpful.On my HPC, however, Seurat is already a module.