MetaboAnalyst: Interpreting Enrichment Analysis Results
0
0
Entering edit mode
21 months ago
eva_u ▴ 10

Hello,

In the Quantitative Enrichment Analysis result table (img1 below): each time I ran the analysis the raw p-values seem to be inversely related to the q-values. How should I interpret this? And which results should I consider significant? E.g. if I go with the standard for raw p-value (<0.05), I'm getting very high (significantly above expected) q-value; if I go with a low q-value, p-value is beyond anything considered to be significant? Could this indicate problem with the data?

Also, for the box plots showing relative abundance of the hit metabolites: all of mine have values above and 0 zero. Should I interpret that as above normal (i.e. reference) abundance and below normal abundance (img2 below)?

Thank you!

Here's an example: QEA results table

enter image description here

enrichment metabolomics • 638 views
ADD COMMENT
0
Entering edit mode

Note: it seems I have confused Q statistic with the Q- value; please disregard the 1st part of the question

ADD REPLY

Login before adding your answer.

Traffic: 1959 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6