Do we have any disease specific SNVs database?

Question

[Nemo]

Hi, I have a general question. I was looking for some resources to bring some connection between SNVs and protein activity. I know that there are some softwares like ANNOVAR which can be used to prioritized the SNVs in terms of their importance. However, specifically I want to know is this correct that we say SNVs are context free in terms of diseases? how are SNPs linked to genes in a context-specific (specific disease) manner?

[Medhat]

The Genome Aggregation Database (gnomAD) is a resource developed by an international coalition of investigators, with the goal of aggregating and harmonizing both exome and genome sequencing data from a wide variety of large-scale sequencing projects, and making summary data available for the wider scientific community.