COG clustering

Question

[Shweta]

How to use COGs for clustering? How to use API? its bit confusing

[seidel]

What are you trying to achieve? COGs are clusters. There are more API's than I can count. Please be more specific about what you would like to do, and where you might be stuck. You might find this guide to asking good questions helpful.

[Shweta]

Hey, Thanks for that, I want to ask how to use the COG database for clustering. I have a set of protein sequences of bacteria and viruses and want to do functional annotation of those proteins, How can I use COG?

[moshi]

If your goal is functional classification (annotation) of protein sequences using the COG database, COGclassifier may be useful.