How would I assess evolutionary estimates between duplicated vs. non-duplicated genes in PAML?
0
0
Entering edit mode
20 months ago
codoncity • 0

Hello,

I have been investigating a four-fold gene duplication in a species. All closely related species only possess a single copy of this same gene. How would I check to see if rates of selection for duplicate copies differ when compared with the single copies found in other species?

I feel like partitioning my tree into two groups (e.g. four duplicate sequences vs. all singles) and then comparing them with a LRT stat wouldn't be valid since PAML would apply different rates of evolution to each group. So I'm a bit stumped.

Anyone have any experience with this?

Cheers.

PAML • 339 views
ADD COMMENT

Login before adding your answer.

Traffic: 1613 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6