Is a human genome file with reference as NCBI37 the same as hg19?
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17 months ago
a5864557 • 0

In other words, are NCBI37 and hg19 synonymous? I can't find much information for what NCBI37 is in a human (not mouse) genome.

Relevant line from VCF: "##reference=NCBI37"

vcf hg19 genome reference-genome • 1.3k views
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Note: I've also asked this here

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Don't cross-post, especially on weekends. It looks like you're in a hurry and you don't care about annoying multiple communities.

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17 months ago
GenoMax 147k

If you go to the GRCh37 page at NCBI you will see that hg19 is a synonym (mostly used by UCSC as I recall): https://www.ncbi.nlm.nih.gov/assembly/GCF_000001405.13/

Description:
    Genome Reference Consortium Human Build 37 (GRCh37)
Organism name:
    Homo sapiens (human)
BioProject:
    PRJNA31257
Submitter:
    Genome Reference Consortium
Date:
    2009/02/27
Synonyms:
    hg19

Mitochondrial genome has some differences according to the past thread: what is the difference between GRCh37 and hg19 ?

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I know GRCh37 is synonymous (with minor differences) with hg19. However, I'm wondering if NCBI37 is synonymous with GRCh37 and hg19. Maybe it's obvious that NCBI37 refers to GRCh37, but I haven't seen it referred to as NCBI37 before today.

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NCBI did not use GRCm37 designation for mouse genome build. As you can see from the table below that can be found here:

enter image description here

NCBI37 should be human genome.

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