Correction for among sample/chromosomes for sequenicng depth, when comparing between samples or animals
0
0
Entering edit mode
17 months ago
mohsamir2016 ▴ 30

Sorry for naive question. I am comparing between 5 animals regarding SNPs, and have counts for each chromosomes that I annotated using GATK (The Genome Analysis Toolkit (GATK) v4.3.0.0). I have also the genotypes being annotated. Now I am afraid that comparing number of SNPs across samples or animals or chromosomes, could be biased by the differences in sequencing depth between these. Is GATK pipleine corrects for sequenicng depth for instance within one VCF file between various chromosomes that might have various depth. If not how can I retrieve these information to plot depth vs n of SNPs per each chromosome ?

Thanks

GATK SNPs • 417 views
ADD COMMENT

Login before adding your answer.

Traffic: 1940 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6