How to find LD matrix for a large group of SNPs (more than 6000 SNPs)
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16 months ago
Phylicia ▴ 10

As the question shows, I want to calculate the LD matrix of 6000 + SNPs with only knowing the rsid of the SNPs.

I have checked that I can use Plink to do it if I have bfile or vcf file, but unfortunately I do not have.

If I use LDlink website I can calculate maximum 300 SNPs while 3000 SNPs with API by R coding.

Do I have option to calculate the LD matrix of 6000 + SNPs with rsid but without other information?

Thank you very much and look forward to your kind help.

SNP LD • 442 views
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