Errors while trying to run Scenic

Question

[Stavroula]

Hello,

I have been trying to runScenic2 but I keep getting the error below:

runSCENIC_2_createRegulons(scenic2, coexMethod=c("top5perTarget"))# Toy run settings
17:06   Step 2. Identifying regulons
[1] "IOError: Failed to open local file '/Users/sp2037/Desktop//NA'. Detail: [errno 2] No such file or directory"
Error in runSCENIC_2_createRegulons(scenic2, coexMethod = c("top5perTarget")) : 
  It is not possible to load the following databses: 
dm6-5kb-upstream-full-tx-11species.mc8nr.feather

Does anybody else has encountered a similar error or anyone willing to provide some feedback?

Thanks

[GenoMax]

"IOError: Failed to open local file '/Users/sp2037/Desktop//NA'. Detail: [errno 2] No such file or directory"

Can you provide the actual command you are trying to run? Looking at the error above it looks like it is not able to find a file for the database.

[Stavroula]

The command is the top line:

runSCENIC_2_createRegulons(scenic2, coexMethod=c("top5perTarget"))

I have double checked that the file has been downloaded correctly.

Thanks

[GenoMax]

Quick look at the scenic manual indicates scenic2 is where you assigned the directory that contains the database files? That may be incorrectly done.