How to adjust kaplan-meier curves for confounding factors and get p value?
0
0
Entering edit mode
13 months ago
Manuel ▴ 10

Following the tutorial from stanford uni , if kaplan meyer curves do not contain significant p value but the coxph for the same variable contains, the curves should adjusted for possible confounding factors. C1, C2, C3 and C4 correspond to other classification of the disease by gene expression.

unadjusted kaplan-meyer

enter image description here

adjusted kaplan-meyer

cox <- coxph(Surv(TIME_TO_DEATH_FROM_SURGERY, Morte.S.N) ~ Histologia +  Transcriptomic + 
Genomic + Sexo +Tratamento.adjuvante , data = clinical_data_clean)
ggadjustedcurves(cox, variable = 'Transcriptomic', data = clinical_data_clean)

Is is possible to add a p value for the second graph with the curves adjusted for confounding factors? And could you provide some feedback about the correctness of this analysis?

Thank you and best regards.

kaplan-meier coxph confounding survivalanalysis • 335 views
ADD COMMENT

Login before adding your answer.

Traffic: 2590 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6