Entering edit mode
14 months ago
Jay
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0
A naive n00b question here. Title says it. We have some tumor samples that we're planning to sequence with a Nanostring 360 panel. We have paired normal for each sample but we also have a lot of samples. Could we get away with running fewer normals and creating a panel of normals or is running paired tumor/normal heavily advised? I've been poking around and can't find anything on this. Thanks!
What is the analysis goal?
Just to discover differentially expressed genes between sets of cancer samples based on methylation status, histology type, etc. We're just looking for genes that stand out between the two groups.