Large qiime2 table (107 gb) to phyloseq
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12 months ago
bala • 0

Hello,

I'm currently engaged in a microbiome meta-analysis and have combined a dada2 table involving data from 83 different studies. The file size of this merged table is 107GB. However, I'm encountering difficulties reading this file in R to conduct statistical analyses.

I've attempted to import the Qiime2 file in QZA format and the table in TSV format. In both instances, RStudio crashed, even when using an HPC with 250GB of RAM.

Do you have any suggestions or know of any packages that might help resolve this issue?

Thank you for your time and any suggestions you can provide.

Many thanks.

phyloseq-reg meta-analysis • 374 views
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