Looking to compute R-squared with P-value for LocusZoom plot
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13 months ago
skjobs ▴ 190

Looking to compute R-squared values for a list of SNPs associated with specific phenotypes. Interested in having both p-values and R-squared scores for each SNP. Any advice on how to do this efficiently? After Rsqure and the p-value. I want to plot the LocusZoom plot. For the LocusZoom plot input should have p-value of SNPs and R2-Squre. Can anyone advise or help me on how to generate it? I'm working on the plink.

CHROM   POS ID  P   R2
chr1    67216513    rs11576518  8.04E-20    1
chr1    67253446    rs1343151   3.13E-19    0.40487769
chr1    67264372    rs6669582   5.65E-19    0.40081561
chr1    67214307    rs2019262   1.10E-18    0.97752769
chr1    67215986    rs7517847   1.31E-18    0.97851664
chr1    67263180    rs11313807  1.96E-18    0.40462321
chr1    67205233    rs2902440   2.73E-18    0.96000804
R plink LocusZoom GWAS • 612 views
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