Trimming reads before running Juicer
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12 months ago
isMM • 0

Hello folks! I have a very basic HiC related question. I am running Juicer on a dataset to get the .hic files, after running FastQC on my data I have realized it has ~10% of comulative adapter contamination at the end (150bp), is it necessary to trim it? Can Juicer run well with the un-trimmed data?

Thanks for the insight!

HiC JUICER QC • 495 views
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I would trim the adapters always to be safe than be sorry later on.

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