Phasing a Single-Sample VCF File on GRCh38
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11 months ago
LuciaNhu • 0

I have created a VCF file using the nf-core sarek / DeepVariant pipeline, which contains data for only one individual. I'm seeking guidance on how to perform phasing for this single-sample VCF file based on GRCh38.

Could someone suggest a tool, workflow, or tutorial specifically suited for phasing a single sample using GRCh38?

I've explored options like SHAPEIT5, Beagle 5.0, and WhatsHap, but unfortunately, they do not seem to work for my scenario.

I appreciate any assistance or recommendations you can provide.

Happy New Year and thank you,

Nhu

GRCh38 imputation phasing DeepVariant • 370 views
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