Tool:GW: fast genome browser and variant exploration tool
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9 months ago
clealk ▴ 70

Hello Biostars,

Please check out our new tool, GW (Genome-Wide), a high-performance genome browser for the analysis and visualisation of aligned sequencing reads and data tracks.

GW supports very fast data rendering and addresses the memory limitations often encountered when visualising large genomic regions. This feature may be useful when dealing with large copy-number variants or complex genome rearrangements.

GW has a lightweight user interface for navigating and quantifying genomics data, and comes with built-in commands for data interaction making it versatile for various analysis tasks.

GW also allows you to manually label variants using image tiles, and save or load annotations over multiple sessions.

Alignment view of GW *'Alignment-view' with a few data-tracks loaded

Whole of chr8 showing complex CNV pattern *An interactive view of the whole of chr8 rendered in 6-7s using a MacBook Pro M2, consuming <1Gb memory. Coloured arcs represent structural variants.

Image-view *Explore + annotate collections of variants using the 'image-view'

  • Multi platform(MacOS, Linux, Windows, Android), CLI or Desktop apps available.
  • Both dynamic and static modes of data visualisation.
  • Support for several color themes.
  • Tools for quantification (e.g. see 'filter' and 'count' commands).
  • Integration with online genomic databases for data comparison.
  • Stream VCF files to GW from other tools (e.g. bcftools) for convienient data exploration.

Documentation:

https://kcleal.github.io/gw/

Repo:

https://github.com/kcleal/gw

visualization genome-browser genome variant-annotation genomics • 425 views
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