The Biostar Herald publishes user submitted links of bioinformatics relevance. It aims to provide a summary of interesting and relevant information you may have missed. You too can submit links here.
This edition of the Herald was brought to you by contribution from Mensur Dlakic, Istvan Albert, and was edited by Istvan Albert,
Genomic data in the All of Us Research Program | Nature (www.nature.com)
he All of Us Research Program is a longitudinal cohort study aiming to enrol a diverse group of at least one million individuals across the USA to accelerate biomedical research and improve human health
All of Us identified more than 1 billion genetic variants, including more than 275 million previously unreported genetic variants, more than 3.9 million of which had coding consequences. Leveraging linkage between genomic data and the longitudinal electronic health record, we evaluated 3,724 genetic variants associated with 117 diseases and found high replication rates across both participants of European ancestry and participants of African ancestry.
submitted by: Istvan Albert
actually he's quite far off. See our detailed alignment of human and chimp in: https://t.co/iOtRucvUCr. TL;DR human and chimp are 98% identical across 96% of their length. More detail in attached screenshot pic.twitter.com/mXkqNYF2yw
— Steven Salzberg 💙💛 (@StevenSalzberg1) February 18, 2024
actually he's quite far off. See our detailed alignment of human and chimp in: https://t.co/iOtRucvUCr. TL;DR human and chimp are 98% identical across 96% of their length. More detail in attached screenshot pic.twitter.com/mXkqNYF2yw
— Steven Salzberg 💙💛 (@StevenSalzberg1) February 18, 2024submitted by: Istvan Albert
Dictionary learning for integrative, multimodal and scalable single-cell analysis | Nature Biotechnology (www.nature.com)
Latest Seurat in action
submitted by: Mensur Dlakic
Announcing uv: an extremely fast Python package installer and resolver, written in Rust.
uv is designed as a drop-in alternative to pip, pip-tools, and virtualenv.
With a warm cache, uv installs are near-instant. Here, it's > 75x faster than pip and pip-tools. pic.twitter.com/wrvaudUn6i
— Charlie Marsh (@charliermarsh) February 15, 2024
Announcing uv: an extremely fast Python package installer and resolver, written in Rust.
uv is designed as a drop-in alternative to pip, pip-tools, and virtualenv.
With a warm cache, uv installs are near-instant. Here, it's > 75x faster than pip and pip-tools. pic.twitter.com/wrvaudUn6i
submitted by: Istvan Albert
A tale of two misassemblies | Ryan Wick’s bioinformatics blog (rrwick.github.io)
[...] we saw two interesting misassemblies that I describe here. Both cases occurred with ONT-only assemblies
submitted by: Istvan Albert
https://academic.oup.com/bioinformaticsadvances/advance-article/doi/10.1093/bioadv/vbae018/7602576
The software and ontology mappings can be obtained from: https://github.com/EBIvariation/CMAT
submitted by: Mensur Dlakic
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