Interprete plot of dispersion estimation by DESeq2

Question

[tien]

Dear all,

I'm working with DEXseq and one of the step is estimating dispersion. I'm using the following command: estimateDispersions(dxd, fitType="local").

I want to analysis the output after this step so I plot dispersion against the mean of normalized count following the tutorial by DESeq2, however, I don't know how to interpret this plot and conclude if the estimation of dispersion is 'reasonable' or 'acceptable'.

May I ask if anyone can instruct me to read this plot?

Thanks in advance for any help.

[Pierre Lindenbaum]

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